Versipelostatin is a macrocyclic compound discovered from the bacterium Streptomyces versipellis 4083-SVS6. It functions as a down-regulator of the grp78 gene, which encodes the molecular chaperone GRP78/BiP, a key player in the endoplasmic reticulum (ER) stress response.
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*FOR RESEARCH USE ONLY. Not for human or veterinary use. This product is intended exclusively for laboratory research and must not be used in diagnostic or therapeutic applications.
Versipelostatin Specifications
| Formula | C₆₁H₉₄O₁₇ |
| Purity | ≥98% |
| CAS Number | 477201-98-2 |
| Solubility | - |
| Storage Temperature | -20°C |
| Shipping Temperature | ambient |
| Molecular Weight | 1099.4 g/mol |
| SMILES | CCC1C2C(C3C(C=C2C)C(O)CC(=O)C3C)(CC)C(=O)C2=C(C3(C(C=C(C(C3)C)C)(C)CCCC(C)C(OC3OC(C)C(OC4OC(C)C(OC5OC(C)C(O)C(O)C5)C(OC)C4)C(O)C3)C(C)CC(CO)C=1)OC2=O)O |
| Synonym | (11S,15E)-11-[(2R,4S,5S,6R)-5-[(2R,4R,5R,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-16,26-diethyl-21,27-dihydroxy-14-(hydroxymethyl)-3,4,6,10,12,18,24-heptamethyl-30-oxapentacyclo[26.2.1.01,6.017,26.020,25]hentriaconta-4,15,18,27-tetraene-23,29,31-trione |
- Park, H.-R., Furihata, K., Hayakawa, Y., & Shin-ya, K. (2002). Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin. Tetrahedron Letters, 43(39), 6941–6945. https://doi.org/10.1016/S0040-4039(02)01624-6
Need additional documentation? Safety Data Sheet, Certificate of Analysis and batch-specific data are available upon request from our technical support team.
Our Versipelostatin Prices
*For custom handling, including aliquoting or specific packaging formats, please get in touch with our technical support team.| Quantity | Cost |
|---|---|
| 500 µg | $630 |
| 1 mg | $1,260 |
| >1 g | Request a Quote |
💡 Bulk Discounts Available: Contact us for custom pricing on orders over 1 mg
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