End-to-End Bioproduction Services for Enzymes, Peptides & Natural Products with IsoZym®
Bringing a promising innovation from the lab to industrial production is not a simple task. Although your team may already have strong science and novel enzymes or strains, transforming these into scalable, reproducible and transferable processes demands more than just great research. This is where our end-to-end bioproduction services, the IsoZym® platform, can help.
Along the way, many research teams encounter common roadblocks:
- Production strains that behave unpredictably at scale.
- Limited expertise in strain and process development, purification or analytical monitoring.
- Limited options due to IP constraints in the USA.
- Resource gaps that slow progression or introduce risk.
This is exactly where IsoZym® can help.
IsoZym® offers bioproduction services designed to support your team from sequence identification to ready-to-scale processes.
Whether you need to strengthen a specific stage of your pipeline or develop a complete process, the platform gives you access to proven tools and expert guidance, without the need to expand your internal infrastructure and resource.
How the IsoZym® Platform Supports Your Project Requirements
At its core, IsoZym® offers two distinct, but complementary, operating modes:
1. Modular Biosolutions:
IsoZym® is composed of specialized technology and service modules, each representing a critical stage in the bioproduction pipeline. These modules are designed to function independently or in any combination. This means clients can engage precisely where they need support; whether it’s rapid enzyme engineering with EvoSelect®, accessing our proprietary IsoChassis™ microbial hosts or leveraging high cell-density pilot fermentation for production-scale trials.
Modular use empowers clients to fill expertise gaps, reduce costs and accelerate specific project phases by accessing only the technologies and expertise needed for each stage.
2. Integrated, End-to-End Workflows:
For teams seeking comprehensive support, IsoZym®operates as a fully integrated bioproduction platform. From sequence design through to scale-up, downstream processing and technology transfer, every step is tightly coordinated by Isomerase’s multidisciplinary team. Data flows seamlessly between modules, timelines are compressed and scientific risks are managed holistically. For example, a client can provide only the native sequence of a target enzyme, and within approximately 8 weeks, Isomerase will deliver a fully optimized sequence and 1–10 grams of material.
Integrated use ensures the highest level of coordination, transparency, and efficiency—especially valuable for complex or resource-limited projects seeking a “bench-to-commercialization” partner.
What Isomerase's Bioproduction Services Offer
Choosing the right partner can make the difference between success and setbacks in moving from research to production.
Isomerase combines the power of the IsoZym® platform with deep scientific and process expertise bringing partners:
- Access to Isomerase’s proprietary database of over 20,000 curated microbial strains and thousands of genome sequences for rapid identification of novel enzymes, biosynthetic pathways and high-performance production strains for a wide range of applications.
- Enzyme engineering with ML-guided engineering tool EvoSelect® for rapid candidate selection.
- A comprehensive suite of IsoChassis™ engineered industrial hosts, including core yeast production platforms such as Pichia pastoris (Komagataella phaffii) and Saccharomyces cerevisiae, as well as bacterial hosts like Escherichia coli and Bacillus subtilis. Supported by proprietary genetic components, these strains enable high-efficiency enzyme, protein and peptide expression and are engineered to address a wide range of applications and industry requirements.
- Strain engineering (including non-GM strain improvement options).
- In-house CRISPR genome editing tools.
- Rapid prototyping with ProteoSynth® cell-free protein synthesis systems.
- Assay development and analytics.
- High-yield fermentation and purification at lab as well as pilot scale.
- Process optimization and industrial-scale readiness, including full tech transfer support to partner CDMO.
- Flexible engagement (modular, integrated, or a combination), tailored to your scientific and business priorities.
- By partnering with Isomerase, your team gains flexible access to this expertise without the need to expand internal infrastructure.
The Benefits of Using IsoZym®
- Reduced timeline from lab to production.
- Robust processes that scale successfully.
- Clear documentation for CDMO transfer.
- Access to proven tools and expert teams.
- Reduced risk at each stage of development.
- We complement your team and help you deliver production ready processes with fewer setbacks.
- Competitive pricing and reduced costs especially true within the US market.
Common Applications of IsoZym® Platform
Partners use the IsoZym® platform for a variety of bioproduction services, including:
- Scaling enzyme production
- Genome mining or discover novel therapeutics
- Building microbial strain production platforms
- Improving existing processes for better yield or transferability
- Preparing processes for CDMO or internal tech transfer
With IsoZym®, teams can address current gaps and to prepare their processes for long term success.
Tailor Bioproduction Services to Your Project Goals
Are you preparing to scale a process, transfer to a CDMO, or build a new production platform?
Collaborate with Isomerase and take advantage of our bioproduction services today.
We have extensive experience working with international partners, with the majority of our clients based in the United States. We welcome inquiries from organizations worldwide to explore potential collaborations.