Isomerase were approached by a chemicals manufacturer looking to generate alternative processes to a range of enzymes for biocatalysis.

• Solution: Development of an enzyme secretion system to allow direct lyophilization of fermentation supernatants

We generated a panel of microbial expression strains with vectors containing a secretion tag. Fermentation was carried out to confirm presence and activity in the broth with cellular material removed. A DSP method was then developed which enabled lyophilised enzyme to be isolated directly from the fermentation broth.

development of strains and processes to generate a secreted enzyme

If you would like to learn more about our capabilities then please get in contact with us here.

Cookies user preferences
All essential cookies are mandatory in order to allow logging in and submitting forms etc. You can choose to decline some non-essential ones.
Accept all
Decline all
Read more
Tools used to analyze the data to measure the effectiveness of a website and to understand how it works.